Arnauld SERGÉ

Aix-Marseille University – Laboratory Adhesion & Inflammation (LAI)

INSERM U1067, CNRS UMR 7333, AMU UM61

163, avenue de Luminy – Case 937, 13288 Marseille Cedex 9, France

labadhesioninflammation.org – orcid.org/0000-0003-4271-3706

Professional experience – Education

Current Associate Professor, LAI, Aix-Marseille University, France

Dynamic videonanoscopy of immune-cancer interactions

2019 HDR – Nanodynamics of Cell Receptors 

2013-2019 Associate Professor, CRCM, Aix-Marseille University, France

Team Junctional adhesion molecules in tumor/host interactions, M Aurrand-Lions

Dynamic study of the molecular processes of the plasma membrane 

2011-2012 Sabbatical, Department of Pathology & Immunology, Geneva Medical Faculty, Switzerland

Team Vascular and leukocyte adhesion molecules and cell migration, Pr BA Imhof

In vivo study of the interactions between lymphocytes and their environment

2003-2010 Assistant Professor, Ciml, Aix-Marseille University, France

Team Membrane dynamics and T lymphocyte signaling, HT He & D Marguet

Membrane dynamics of the EGFR – multiple target tracing

2001-2003 Postdoctoral training, Physics department, Leiden University, the Netherlands

Team Physics of life processes, Pr T Schmidt

Dynamic reorganisation of the plasma membrane on single molecule stimulation, in vivo

1997-2001 PhD in neurobiology, Bordeaux University, France

Team Cellular physiology of the synapse, supervisor: D Choquet

Membrane mobility of glutamate receptors

1995 – 1996 Master degree in Physics – Biology interface, Orsay, France

UMR421 Créteil, M Peschanski

Effect of kainate in the hippocampus studied by differential display

1993 – 1996 École Supérieure d’Électricité, Gif-sur-Yvette, France

1996 – 1997 Auditor of the Neurosciences Master degree

Paris VI, France

1991 – 1993 Preparatory classes to higher French engineer schools

Lycée Hoche, Versailles, France

1991 Baccalaureate in Mathematics grade B

Lycée J Monnet, La Queue-lez-Yvelines, France

Student supervision

LAI Marseille, France

  • Loriane Maillot, M2 Biology-Health. 2021

CRCM Marseille, France

  • Margaux Haering, M1 Bioinformatique. 2019
  • Oksana Gorshkova, DOC2AMU PhD. 2016 – 2019
  • Fida Rebaï, M2 INSA Tunis. 2016
  • Jean-Charles Cancel, M1 Immunology. 2015
  • Emie Martin Gerber, TIPE – MP*1, Lycée Thiers. 2015
  • Jessica Cappaï, M1 & M2 Pro Oncology. 2014 – 2015
  • Laurence Willemet, École d’Ingénieur des Mines, Gardanne. 2015
  • Céline Bouix, M2 BBSG. 2014
  • Anne-Laure Bailly, PhD in Immunology. 2013 – 2016
  • Céline Mourareau, M2 Immunology. 2013

CMU Geneva, Switzerland

  • Romain Ballet, PhD in Immunology.  2011 – 2015
  • Jeanne Guénot, M2 Immunology. 2011
  • Mehdi Meguenani, PhD in Immunology.  2008 – 2013

CIML Marseille, France

  • Vincent Rouger, PhD in Immunology. 2009 – 2013
  • Louis-Baptiste Jaunay, M2 Medicine. 2009
  • Marie-Claire Blache, Professional License Biophysics. 2007 – 2008
  • Gilles Rousserie, M2 Immunology. 2006
  • Axel Defays, M2 Immunology. 2006
  • Simon Pigeon, M2 Imaging – INSA Rennes. 2006

Leiden Institute of Physics, the Netherlands

  • Sandra de Keijzer, PhD in Biophysics. 2002 – 2007
  • Piet Lommerse, PhD in Biophysics. 2001 – 2005

Prizes / Distinctions

  • Prime of Doctoral Supervision and Research (PEDR), 2017-2021
  • Sabbatical for Research or Thematic Conversion (CRCT), January-June 2016
  • Prime of Scientific Excellence (PES), 2014-2017
  • Installation award – city of Marseille, 2004
  • PhD prize of the French Neurosciences Society, 2003
  • Prize of the best poster of the club exocytose in Arcachon, 2001

Funding

LAI

  • Welcome Grant Interdisciplinary Master (AMI) GdR Imabio (coordinator) for the M2 internship of Loriane Maillot, January-June 2021
  • Project Emergence Cancéropôle PACA (partner) 2021

CRCM

  • Project FUI C-Blue (partner) 2019-21

Highly dynamic, low noise imaging solution

Partnership with First Light Imaging, Exavision, Photon lines, CNRS (Dr. S Monneret)

  • DOC2AMU PhD grant, co-initiator, 2017-20

Nanodynamic Imaging of Leukemic Cell Adhesion, collab. S Monneret & FLI

  • Project ARC Foundation, project initiator, 2014-15

Dynamic videonanoscopy of junctional adherence molecules in physiological and tumoral context  

  • FRM Urgence de la Recherche (partner) 2013-15

Physchem4biomed: Bioinformatics analysis for research in biology

Geneva University

  • Oncosuisse research contract, Swiss National Foundation 2012-13, with Pr. Beat Imhof, CMU Genève

Novel molecules for tumor treatment: angiogenesis, lymph-angiogenesis, pericytes and immune cells

Ciml

  • ANR blanc nanoDIGICODE contract (partner) 2010-14

Deciphering the molecular dynamics & organization of the Ras signaling node in the control of the analog/digital signal processing

  •  ANR blanc MnemoSig contract (partner) 2005-8

Functional memory of the plasma membrane: regulating cell activation thresholds

Post-doctorate 

  • European Marie-Curie fellowship
  • EMBO fellowship

PhD

  • Ministère de la Recherche (MRT) fellowship
  • Fondation pour la Recherche Médicale (FRM, 4th year)

Expertise

  • Representative of the LAI for the Cancer and Immunology Institute, current
  • Representative of the CRCM for the Marseille Imaging Institute, 2013-2019
  • Coordinator of CRCM imaging projects with the PACA Canceropole, 2013-2019
  • Member of the Steering Committee of the CRCM Imaging Platform, 2013-2019
  • Member of the GdR ImaBio, Group of Research Imaging and Microscopy in Biology
  • Member of the GDR AQV, Approches quantitatives du vivant
  • Peer review of Nature Communication, Biophysical Journal, JoVE and PLoS One, Oncotarget manuscripts
  • Expertise of ANR, Région Ile-de-France and Ecos Sud Argentine projects
  • Participation to juries of assistant Pr (MCU) recrutement concours:
    • CRCM, 2019, 2021
    • Institut Fresnel, 2008
  • Participation to thesis juries:
    • Xuan Luo, In vitro quantitative study of T cell adhesive haptotaxis, dir. Olivier Théodoly, Marseille 2019
    • Matthieu Lagardère, Développement d’un Simulateur fondé sur la Dynamique Brownienne de molécules individuelles et dédié à l’Imagerie de Fluorescence sur Cellules Vivantes, dir. Olivier Thoumine, Bordeaux 2017
  • Member of thesis committees:
    • Brice Chanez, Role of +TIPs in the migration and invasion of tumor cells, CRCM 
    • Vladimir Lalentin, Study of The Mechanism of Acute Myeloid Leukemia Immune Escape from NK Cell Immune Control, CRCM
  • Chair of the baccalaureate jury in 2006 and 2016